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. Author manuscript; available in PMC: 2013 Jul 1.

Published in final edited form as: Arch Biochem Biophys. 2012 Mar 15;523(1):77–86. doi: 10.1016/j.abb.2012.03.003

TABLE 5.

Effect of dietary calcium on unoccupied VDR content in rat duodenum and kidney

		Day

	Diet	2	7	14	21
VDR
Duodenum	1% calcium	341±26	197±17	202±17	259±26
	0.02% calcium	365±27	226±28	221±16	267±28
Kidney	1% calcium	ND	163±11	165±9	124±8
	0.02% calcium	ND	120±4^*	131±10^*	77±3^*
Calcium (mg/dL)	1% calcium	9.98±0.18	9.82±0.08	9.16±0.16	9.52±0.41
	0.02% calcium	9.45±0.12	9.15±0.17^*	9.09±0.14	8.70±0.29^*
Phosphorus (mg/dL)	1% calcium	8.40±0.17	8.88±0.22	8.73±0.17	7.92±0.29
	0.02% calcium	8.15±0.22	8.65±0.13	8.37±0.28	8.41±0.23
1α, 25-(OH)₂D₃ (pg/mL)	1% calcium	153±11	113±13	139±9	160±32
	0.02% calcium	180±20	392±45^**	682±44^**	829±59^**

Values are mean ± SEM.

Unoccupied vitamin D receptor content expressed as fmols [³H]1α,25(OH)₂D₃ bound per mg cytosol protein.

^*

P<0.05;

^**

P<0.001.

ND = not done.

Modified from Goff JP, et al[224]