Table 2. Multivariate analysis of hematoma expansion in lobar ICH.

Variable*	OR (95% CI)	p – value
Age	1.00 (0.96 - 1.05)	0.80
Sex	0.62 (0.25 - 1.53)	0.30
Hypertension	1.32 (0.54 - 3.29)	0.54
Warfarin	4.44 (1.19 - 17.63)	0.034
Antiplatelet therapy	0.62 (0.25 - 1.53)	0.32
Time to imaging:
< 6 hours	Ref.	Ref.
6 – 12 hours	0.58 (0.18 - 1.86)	0.36
< 24 hours	0.81 (0.30 - 2.19)	0.69
Interscan time:
< 6 hours	Ref.	Ref.
6 – 24 hours	0.47 (0.17 - 1.26)	0.13
> 24 hours	0.60 (0.24 - 1.52)	0.28
Baseline ICH volume
< 30 cc	Ref.	Ref.
30 – 60 cc	1.81 (0.60 - 5.55)	0.28
> 60 cc	2.63 (0.44 - 14.28)	0.29
Intraventricular extension	0.44 (0.18 - 1.09)	0.079
APOE ε2	2.72 (1.19 - 6.23)	0.009
APOE ε4	0.71 (0.30 - 1.64)	0.42

^*Analysis adjusted for: age, sex, hypertension, warfarin use, antiplatelet therapy, baseline ICH volume, intraventricular extension, interscan time

OR = Odds Ratio; 95% CI = 95% Confidence Interval; Ref. = reference; APOE = Apolipoprotein E