Table 2.

Hazard ratios for all stroke and its subtypes associated with age-related macular degeneration (AMD)

		All stroke			Cerebral infarction			Intracerebral haemorrhage
	Person- years	No. of cases	HR (95% CI)*	HR (95% CI)†	No. of cases	HR (95% CI)*	HR (95% CI)†	No. of cases	HR (95% CI)*	HR (95% CI)†
No AMD (n = 11625)	151,680.81	574	Reference	Reference	510	Reference	Reference	50	Reference	Reference
AMD (n = 591)	7,406.57	45	1.48 (1.09–2.01)	1.51 (1.11–2.06)	38	1.40 (1.01–1.95)	1.42 (1.01–1.99)	7	2.67 (1.20–5.92)	2.64 (1.18–5.87)
Early AMD (n = 576)	7,244.80	45	1.53 (1.13–2.07)	1.56 (1.15–2.13)	38	1.44 (1.04–2.01)	1.47 (1.05–2.06)	7	2.72 (1.23–6.05)	2.72 (1.22–6.06)

^*Hazard ratio (95% confidence intervals) adjusted for age, gender, race and field center

^†additionally adjusted for mean arterial blood pressure, anti-hypertensive medications, fasting glucose, total cholesterol, HDL-cholesterol, triglyceride levels, body mass index, atrial fibrillation, white blood cell count, cigarette smoking and alcohol consumption status.