Table 2. whole brain comparisons of cortical thickness and area in controls, high-risk people and schizophrenia patients.

Left hemisphere	Cortical Thickness	Cortical Surface Area
S vs. N	Significant decrease in large amount of regions of frontal and temporal lobe, and some occipital and parietal lobe in S	Significant decrease in some regions of parietal lobe and slight increases in temporal lobe in S
S vs. H	Significant decrease in frontal and temporal lobe, and some in parietal lobe in S	Slight decrease in frontal and parietal lobe in S
H vs. N	Regional increase in temporal-occipital, frontal and parietal lobe in H	Slight increase in parietal lobe in H
Right hemisphere	Cortical Thickness	Cortical Surface Area
S vs. N	Mostly frontal reduction with some temporal and parietal reduction in S	Slight parietal reduction and slight increase in frontal and occipital lobe in S
S vs. H	Mostly frontal and temporal reduction with some parietal reduction in S	Slight, scattered frontal, parietal reduction and slight increase in frontal lobe in S
H vs. N	Slight, scattered increase in frontal, temporal, occipital and parietal regions in H	Slight reduction in frontal lobe and slight increase in parietal lobe in H

S=schizophrenia patients; H=high-risk people; N=normal controls