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. 2012 Apr 12;5:73. doi: 10.1186/1756-3305-5-73

Table 1.

The results of 5 independent experiments are summarised

Trial 100 nM Imidacloprid 50 nM Flumethrin 100 nM Imidacloprid + 50 nM Flumethrin Synergism

Trial Amp[μV] cps Amp[μV] cps Amp[μV] cps
05-05 75 75 - 5 150 100 ++

21-05a 50 58 - 5 100 89 ++

21-05b 50 75 - 10 70 100 ++

25-05a 50 80 10 40 100 90 +/-

25-05b 70 50 - 10 100 80 ++

mean 59 67.1 - 14 104 91.8

SD 12.45 12.9 - 14.75 28.81 8.44

P* [vs combination of Flu/Imi] 0.009 0.003 na 0.0007 - -

The isolated nerve cord fibres of Spodoptera frugiperda were stimulated with 100 nM imidacloprid, 50 nM flumethrin and then a combination of these two compounds and the amplitude of nerve discharge and the number of discharges (counts per second, cps) are given. Imidacloprid alone had a modest effect, flumethrin alone had a negligible effect and the combination of both compounds together demonstrate a clearly synergistic effect well in excess of what either compound alone induced

* Normality and two-sided paired t-test was perfomed for all data from five trials using SigmaPlot for Windows 11.0 (Build 11.0.0.75, © 2008 Systat Software, Inc.)