Table 2.

Bipolar proband parent characteristics and history of suicidal ideation in offspring

Bipolar Proband Parent Characteristic	History of suicidal ideation in offspring
	No (N=123)	Yes (N= 110)	p-value
Demographics
Female	99 (80.5%)	88 (80%)	0.9
Caucasian	107(87%)	99 (90%)	0.5
Married	62 (50.4%)	52 (47.3%)	0.7
Age	39.7 ± 8.0	39.5 ± 7.2	0.9
Socio-economic status (SES)a	36.6 ± 14.2	32.6 ± 14.3	0.03
Clinical Characteristics
Bipolar subtype (BPI)	82 (66.7%)	77 (70%)	0.6
Age of bipolar disorder onset	35.8 ± 9.3	36.4 ± 8.7	0.7
Age of first major depressive episode	19.0 ± 8.0	19.4 ± 8.6	0.7
Comorbid Conditions
Anxiety disorder	86 (69.9%)	82 (74.5%)	0.4
Attention deficit hyperactivity disorder	23 (18.7%)	37 (33.6%)	0.009
Substance use disorder	72 (58.5%)	77 (70%)	0.07
Disruptive behavior disorder	34 (27.6%)	47 (42.7%)	0.016
Axis II (borderline or antisocial)	21 (33.9%)	23 (31.9%)	0.8
Lifetime Suicidality
Suicidal ideation	47 (38.5%)	51 (48.6%)	0.1
Suicide attempt	37 (30.6%)	41 (37.3%)	0.3
Lifetime History of Abuse
Physical abuse	28 (24.1%)	31 (29.8%)	0.3
Sexual abuse	41 (34.5%)	42 (40.8%)	0.3
Clinical Characteristics
Aggression (AQb Total score)	83.4 ± 26.4	92.4 ± 27.9	0.02
Current global functioning (GAFc)	64.0 ± 13.3	59.5 ± 11.0	0.005
Most severe past global functioning (GAF)	32.9 ± 13.8	33.5 ± 13.4	0.7

^aHollingshead four-factor criteria (1975)

^bAggression Questionnaire

^cGlobal Assessment of Functioning