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. Author manuscript; available in PMC: 2012 May 29.
Published in final edited form as: Adv Exp Med Biol. 2012;727:305–319. doi: 10.1007/978-1-4614-0899-4_23

Figure 1.

Figure 1

Depiction of Notch pathway and loci at which current and experiemental inhibitors block. Abbreviations: NPR- negative regulatory region; NICD- Notch intracellular domain; ASI- alpha-secretase inhibitor; GSI- gamma-secretase inhibitor; MAML- Mastermind-like; HAT- Histone acetyl-transferase