Table 1.

IC₅₀ values (µM) for compounds 9–13 tested against MCF-7 (ER+) and MDA-MB231 (ER−) human breast cancer cell lines, and Ishikawa human endometrial cells.

Compounds	MCF-7	IC50 values (µM) MDA-MB231	Ishikawa
	10.9	13.9	40.6
	16.5	12.3	18.3
	48.3	33.5	41.8
	10.1	17.0	26.2
	10.3	12.4	15.6
RAL-HCl	0.66	32.8	28.0
4-OHT	1.2	7.8	8.3
TAM	26.2	18.7	33.0

¹The data represent the average of triplicate determinations at various concentrations.

²The IC₅₀ values were determined from the graphs (GraphPad Prism) using mean values of data points at various concentrations.