Fig. 6.
MuRF1 and MAFbx expression patterns after denervation are similar between GRloxP and MGRe3KO mice. A: Northern blot of MuRF1 expression in TS muscle of C57BL/6 mice from either contralateral (Contra) or denervated (Den) limbs (n = 3). A methylene blue stain of the membrane was used to demonstrate equal RNA loading. Gene expression changes for MuRF1 (B) and MAFbx (C) in 1- and 14-day Den and Contra (nondenervated) TS muscles. Dashed lines represent the level of 1-fold change, i.e., no change in expression relative to unoperated controls. Error bars represent means ± SD of n = 3 animals/group. *P < 0.05 (vs. control).