Fig. 1.

Intraperitoneal glucose tolerance test: 4-wk-old ob/ob and ob/ob-cholesterol ester hydrolase transgenic (CEHTg) mice (littermates) were fed chow diet supplemented with 0.2% cholesterol for an additional 4 wk. After an overnight fast, blood glucose levels at time 0 were determined using a commercial glucometer. Subsequently, mice were given an intraperitoneal bolus of glucose (0.5 mg/g body wt), and blood glucose levels were determined at indicated times. Data are expressed as means ± SD; n = 6. *P < 0.05.