Fig. 5.
A: a plot of the cumulative number of open channels (N) and open time probability (Po) from an N2a-Cx43 cell pair that exhibited a maximum of 3 open gap junction channels. On average, 1.83 Cx43 channels were open during the 1-min control period before 1 μM ionomycin + 1.8 mM CaCl2 perfusion. N·Po declined to zero in <5 min of ionomycin/CaCl2 perfusion. B: Cx43 gap junction channel currents recorded during the +45 mV, 5-s baseline control (T1), declining Gj (T2), and the final phase (T3) transjunctional voltage (Vj) pulses. The cumulative N·Po values were 1.67, 1.27, and 0 open channels per unit time, respectively. Value is mean ± SD.