Table 2.

(a) OR (95% CI) for incidence of leukoaraiosis. (b) OR (95% CI) for severity of white-matter lesions.

Multivariate logistic regression analysis
	(a) OR (95% CI)	(b) OR (95% CI)
Adjusted for gender, BMI, ever smoking, hypertension, diabetes mellitus, hyperlipidemia, medication use, acetylsalicylic acid, clopidogrel, beta blockers, calcium blockers, ACE inhibitors, ARBs, HMG-CoA reductase inhibitors, stroke history, stroke etiology	for Leukoaraiosis occurrence	for severity of white matter lesions
Age, years	1.043 (1.012–1.075), P = 0.006	1.065 (1.027–1.103), P = 0.001
IMT above median (0.65 mm)	2.503 (1.181–5.302), P = 0.017	3.012 (1.315–6.897), P = 0.009

OR indicates odds ratio; CI: confidence interval; BMI: body mass index; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blockers; HMG-CoA, 3-hydroxy-3-methylglutaryl-Coenzyme A; IMT: intima-media thickness.