Table 4.
Bivariate Analyses: Predictors of GERD Among Subjects with fILD
| Predictor | Odds Ratio (95% CI) | p |
|---|---|---|
| Age | 0.91 (0.80–1.03) | 0.1 |
| Male gender | 3.10 (0.69–14.08) | 0.1 |
| BMI | 0.98 (0.89–1.08) | 0.7 |
| FVC% | 1.02 (0.97–1.06) | 0.5 |
| DLCO% | 1.04 (0.98–1.10) | 0.2 |
| IPF diagnosis | 6.84 (1.36–34.43) | 0.02 |
| 6MWD | 1.00 (0.99–1.00) | 0.1 |
| Nadir SpO2 during 6MWT | 1.12 (0.87–1.45) | 0.4 |
| Daily supplemental O2 use | 0.65 (0.15–2.89) | 0.6 |
| Prednisone use | 3.20 (0.35–29.00) | 0.3 |
| Reported GERD symptoms | 1.03 (0.10–10.55) | 0.9 |
| Daily anti-reflux therapy | 3.31 (0.60–18.19) | 0.2 |
| Has OSA | 0.35 (0.09–1.48) | 0.2 |
| AHI | 1.00 (0.97–1.02) | 0.7 |
| RERA | 0.98 (0.92–1.05) | 0.6 |
| Nadir SpO2 during PSG | 1.08 (0.98–1.18) | 0.1 |
BMI=body mass index; FVC%=percent predicted forced vital capacity; DLCO%=percent predicted diffusing capacity of the lung for carbon monoxide; IPF=idiopathic pulmonary fibrosis; SpO2=peripheral oxygen saturation; 6MWD=distance walked during the 6-minute walk test (6MWT); GERD=gastroesophageal reflux disease; OSA=obstructive sleep apnea; AHI=apnea hypopnea index; RERA=respiratory event arousal index; PSG=polysomnogram