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Fluid intake (A), urine output (B), and mean blood pressure (C), up to 120 h of life, in preterm baboons in the Untreated, Ibuprofen, and ibuprofen plus nitric oxide synthase inhibitor (Ibu+NOSi) groups. Arrows mark the starting point for ibuprofen administration (24 h; Ibuprofen and Ibu+NOSi groups) and NOSi administration (50 h; Ibu+NOSi group). Values are means ± SE. PT, PA, and PTxA refer to results of ANOVA for treatment, age, and interaction. *P < 0.05 Ibu+NOSi vs. Untreated.
