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Altered levels of hepatic and biliary bile acids result in less susceptibility to hepatic injury after BDL in Nrf2−/− mice. A, B, and C: serum, total hepatic, and biliary bile acid concentrations in sham-operated and BDL wild-type and Nrf2−/− mice. Serum bile acid was below detection levels in sham-operated mice. Values are means ± SD of 5–6 animals. Multiple comparisons were made. *P < 0.05.
