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Upregulation of the mRNA expression of Farnesoid X Receptor (FXR), SHP (prototypical target gene of FXR), Pregnane X Receptor (PXR), and Cyp3a11 (prototypical target gene of PXR) in neonatal wild-type mouse livers. Total RNA was isolated from liver at each age and analyzed by the bDNA assay as described in materials and methods. Data are presented as mean RLU ± SE (n = 5 animals). *Significant differences (P < 0.05) compared with values at day −2 of age.
