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. 2012 Feb 23;302(10):G1111–G1132. doi: 10.1152/ajpgi.00519.2011

Table 3.

Genes upregulated specifically in Sox9-EGFP High cells

Symbol Gene Name Fold Change ID
NTS neurotensin 101.80 67405
TAC1 tachykinin, precursor 1 60.44 21333
CHGB chromogranin B (secretogranin 1) 56.17 12653
CCK cholecystokinin 24.96 12424
GCG glucagon 23.36 14526
CHGA chromogranin A (parathyroid secretory protein 1) 22.31 12652
SCT secretin 17.95 20287
GIP gastric inhibitory polypeptide 16.23 14607
GHRL ghrelin/obestatin prepropeptide 3.46 58991
SOX9 SRY-box containing gene 9 12.03 20682
BMI1 Bmi1 polycomb ring finger oncogene 2.65 12151
HOPX HOP homeobox 4.15 74318

Endogenous Sox9 was specifically highly enriched in the cells ecpressing high levels of Sox9-EGFP (Sox9-EGFP High cells; bold font). Enteroendcrine cell (EEC) markers, as well as BMI1 and HOPX (bold font), 2 markers of slowly cycling or quiescent ISCs (54, 61), were also specifically enriched in Sox9-EGFP High cells. Fold change is expressed vs. gene expression in Sox9-EGFP Negative cells.