Fig. 4.

Immunolocalization of mucosal immune-competent cells and calcitonin gene-related peptide (CGRP) in the murine distal colon. F4/80-immunoreactive (IR) iMϕand CD11c-IR intestinal dendritic cells (red) were identified in close proximity to CGRP-IR nerve fibers (green) in colonic mucosa (area bordered by dashed lines). Boxed fields in the merged micrographs were magnified in the far right column. Arrows indicate mucosal immune-competent cells and CGRP-IR nerve fibers in contact or juxtaposition. Bar indicates 10 μm in the magnified micrographs and 50 μm in the others.