Table 2.
Pre-atenolol |
Post-atenolol |
|||||
---|---|---|---|---|---|---|
Group | n | Body Wt, g | MAP, mmHg | HR, beats/min | MAP, mmHg | HR, beats/min |
CON | 6 | 440 ± 11 | 125 ± 7 | 360 ± 12 | 113 ± 8 | 315 ± 7# |
OR | 5 | 448 ± 3 | 115 ± 6 | 367 ± 14 | 113 ± 6 | 338 ± 12# |
OP | 5 | 538 ± 8*† | 112 ± 9 | 376 ± 8 | 104 ± 7 | 315 ± 13# |
Values are means ± SE; n, no. of animals. Body weight was greater in OP vs. CON (*P < 0.05) and OR (†P < 0.05). There were no significant differences in baseline MAP and HR between groups. Atenolol significantly decreased HR in all groups (#P < 0.05 vs. pre-atenolol).