Fig. 3.

Maternal mean arterial blood pressure (BP) and maternal and fetal heart rates (HR) during constant 20 min intravenous infusion of saline (i.e., basal state) and of serotonin [5-hydroxytryptamine (5-HT); 8 μg·min⁻¹·kg body wt⁻¹] to baboons untreated (n = 5) or treated with estradiol on days 25–59 of gestation (n = 6). *P < 0.05 vs. respective basal maternal BP and HR values; **P < 0.01 vs. the untreated basal maternal BP value; +P < 0.01 vs. the respective basal fetal HR value; ++P < 0.001 vs. untreated 5-HT-infused and estradiol-treated basal fetal HR values.