Table 2.
Comparison of body weight, heart weight, blood pressure, heart rate, and complete blood count between cPLA2α+/+ and cPLA2α−/− male mice at baseline (12 wk old)
| cPLA2α+/+ | cPLA2α−/− | |
|---|---|---|
| Body wt, g | 25.9 ± 1.7 | 24.2 ± 1.8 |
| Heart wt, mg | 116 ± 7.4 | 124 ± 6.5 |
| Heart wt/body wt, ×10−3 | 4.93 ± 0.14 | 5.07 ± 0.17 |
| sBP, mmHg | 83.1 ± 1.8 | 89.1 ± 4.6 |
| dBP, mmHg | 53.5 ± 6.4 | 52.3 ± 5.3 |
| HR, beats/min | 680 ± 12 | 683 ± 14 |
| WBC, μl−1 | 2,686 ± 435 | 2,969 ± 473 |
| Platelet, ×104/mm3 | 41.6 ± 10 | 46.0 ± 11 |
| RBC, ×104/mm3 | 907.1 ± 14.7 | 962 ± 14.8 |
| Hb, g/dl | 13.6 ± 0.60 | 14.1 ± 0.40 |
| Hct, % | 48.8 ± 1.6 | 51.3 ± 1.6 |
Data are expressed as means ± SE; n = 5 mice in each group. cPLA2α+/+, knockout cPLA2 mice; cPLA2α−/−, wild-type cPLA2 mice; sBP, systolic blood pressure; dBP, diastolic blood pressure; HR, heart rate; WBC, white blood cell; RBC, red blood cell; Hb, hemoglobin; Hct, hematocrit; There was no significant difference in each parameter between the 2 genotypes.