Table 2.
NQO1+/+ |
NQO1−/− |
|||||
---|---|---|---|---|---|---|
Room air (n = 10) | Rotenone (n = 4) | Hyperoxia (n = 6) | Room air (n = 8) | Rotenone (n = 4) | Hyperoxia (n = 5) | |
Age, days | 85 ± 8 | 99 ± 3 | 90 ± 12 | 71 ± 7 | 74 ± 5 | 81 ± 6 |
Body weight, g | 25.4 ± 0.8 | 24.9 ± 0.7 | 24.6 ± 0.6 | 25.5 ± 1.2 | 25.3 ± 1.7 | 26.8 ± 1.1 |
Hematocrit, % | 43.0 ± 1.1 | 46.6 ± 2.5 | 48.3 ± 1.7 | 45.0 ± 0.8 | 40.9 ± 2.1 | 47.0 ± 2.9 |
Lung dry weight, mg | 27.1 ± 0.7 | 27.8 ± 1.6 | 29.6 ± 1.2 | 27.3 ± 0.7 | 29.6 ± 0.9 | 31.4 ± 1.0* |
Lung wet-to-dry weight ratio | 5.4 ± 0.1 | 5.5 ± 0.1 | 5.6 ± 0.2 | 5.4 ± 0.1 | 6.0 ± 0.2 | 5.7 ± 0.1 |
Values are means ± SE.
Significantly different from NQO1+/+ room air (1-way ANOVA and Tukey's post hoc test for multiple pairwise comparisons).