Fig. 1.
Effect of treatment with NH4Cl on right ventricular systolic pressure (RVSP) and left ventricular systolic pressure (LVSP) in hypoxic and monocrotaline (MCT)-treated rat models of pulmonary hypertension (PH). A: representative RVSP tracings from individual rats. B: RVSP cumulative data. C: LVSP cumulative data. Data represent means ± SE from 6–12 rats per experimental group. *Measurements in hypoxic or MCT-treated rats are significantly different (P < 0.05) from the corresponding measurements in control normoxic or vehicle-treated rats. #Measurements in NH4Cl-treated hypoxic or MCT rats are significantly different (P < 0.05) from the corresponding measurements in hypoxic or MCT rats without NH4Cl treatment. w/o, Without.