Fig. 10.
Sodium nitroprusside (SNP)-induced relaxation in pulmonary and mesenteric artery of normoxic, hypoxic, and MCT-treated rats with or without treatment with NH4Cl (acidosis). Pulmonary artery (A) and mesenteric artery segments (B) were precontracted with Phe (10−5 M), increasing concentrations of SNP were added and the % relaxation of Phe contraction was measured. Data represent means ± SE (n = 6–8). *Measurements in hypoxic and MCT-treated rats are significantly different (P < 0.05) from corresponding measurements in normoxic rats. #Measurements in NH4Cl-treated (acidosis) rats are significantly different (P < 0.05) from corresponding measurements in hypoxia or MCT-treated rats without NH4Cl treatment.