Fig. 8.

ACh-induced relaxation in pulmonary and mesenteric artery rings of control normoxic, hypoxic, and MCT-treated rats with or without treatment with NH₄Cl (acidosis). Pulmonary artery (A) and mesenteric artery segments (B) were precontracted with Phe (10⁻⁵ M), increasing concentrations of ACh were added and the % relaxation of Phe contraction was measured. Data represent means ± SE (n = 6–8). *Measurements in hypoxic and MCT-treated rats are significantly different (P < 0.05) from corresponding measurements in control normoxic rats. #Measurements in NH₄Cl-treated (acidosis) rats are significantly different (P < 0.05) from corresponding measurements in hypoxia or MCT-treated rats without NH₄Cl treatment.