Table 1.

Body weight, arterial pH, blood gas, and hematocrit in control normoxic, hypoxic, and MCT-treated rats with or without treatment with NH₄Cl (acidosis)

Parameter	Normoxia	Normoxia+Acidosis	Hypoxia	Hypoxia+Acidosis	MCT	MCT+Acidosis
Body weight, g	293 ± 12.5	291 ± 16	289 ± 10	243 ± 11†	373 ± 12	363 ± 5
Arterial pH	7.37 ± 0.01	7.32 ± 0.03	7.29 ± 0.01*	7.08 ± 0.02†	7.36 ± 0.01	7.26 ± 0.04†
Pco2, mmHg	52 ± 0.9	48 ± 1.8	45 ± 2	40 ± 1.8	49.4 ± 1.3	44.8 ± 2.1
Plasma HCO3−	28.8 ± 0.6	24.6 ± 1.9	21.2 ± 0.6*	11.8 ± 0.6†	27.5 ± 0.7	19.5 ± 1.7†
Hematocrit, %	38.5 ± 1.2	36.5 ± 0.8	63.3 ± 2.3*	66.1 ± 2.4*	42 ± 1	43.2 ± 1.3

Data represent means ± SE of cumulative data from 6–12 rats.

^*Measurements in hypoxia or monocrotaline (MCT)-treated rats are significantly different (P < 0.05) from corresponding measurements in normoxic rats.

^†Measurements in NH₄Cl-treated (acidosis) rats are significantly different (P < 0.05) from corresponding measurements in normoxic, hypoxic, or MCT rats without NH₄Cl treatment.