Table 2.
Echocardiographic assessment of WT mice
| LV M-Mode | NP (n = 9) | MP (n = 9) | LP (n = 8) |
|---|---|---|---|
| LV AW, mm | |||
| Diastolic | 0.74 ± 0.02 | 0.79 ± 0.05 | 0.82 ± 0.05 |
| Systolic | 1.10 ± 0.06 | 1.11 ± 0.05 | 1.08 ± 0.05 |
| LV PW, mm | |||
| Diastolic | 0.64 ± 0.04 | 0.68 ± 0.02 | 0.65 ± 0.02 |
| Systolic | 1.03 ± 0.06 | 1.08 ± 0.06 | 0.96 ± 0.02 |
| LV diameter, mm | |||
| Diastolic | 3.86 ± 0.03 | 4.02 ± 0.03* | 4.00 ± 0.06 |
| Systolic | 2.50 ± 0.07 | 2.61 ± 0.08 | 2.87 ± 0.03*† |
| LV volume, mm3 | |||
| Diastolic | 64.24 ± 1.12 | 71.11 ± 1.43* | 70.08 ± 2.44 |
| Systolic | 22.69 ± 1.65 | 25.16 ± 1.90 | 31.41 ± 0.92*† |
| LV %EF | 64.85 ± 2.18 | 64.58 ± 2.63 | 54.99 ± 1.37*† |
| LV %FS | 35.14 ± 1.67 | 35.16 ± 1.20 | 28.21 ± 1.92*† |
Values are expressed as means ± standard error of mean (SE) n = number of mice per group. AW, anterior wall; PW, posterior wall; EF, ejection fraction; FS, fractional shortening.
*
P ≤ 0.05, significantly different from NP;
†
P ≤ 0.05, significantly different from MP.