Table 3.

Cox regression model analysis for disease-free survival in the intent-to-treat population

	Univariate		Multivariate
Characteristics	HR (95% CI)	P	HR (95% CI)	P
Treatment
D→EC versus EC	0.99 (0.73–1.31)	0.95
Age
>50 versus ≤50 years	1.11 (0.84–1.46)	0.47
T size
T2–T3 versus T1	1.84 (1.36–2.49)	<0.0001	1.80 (1.33–2.44)	<0.0001
N involvement
≥4 versus 1–3	1.15 (0.61–2.17)	0.67
Histopathological grade
G3 versus G2	1.41 (1.04–1.91)	0.01
Hormonal receptor status
Positive versus negative	0.48 (0.36–0.64)	<0.0001	0.49 (0.36–0.66)	<0.0001
HER-2 status
Negative versus positive	0.54 (0.36–0.81)	0.004
Adjuvant radiotherapy
Yes versus no	1.00 (0.74-–1.35)	0.98

CI, confidence interval; D, docetaxel; EC, epirubicin plus cyclophosphamide; HR, hazard ratio; N, node; T, tumor.