Table 2.
Demographic data and clinical and pathologic parameters of patients with anti-glomerular basement membrane disease
| Parameter | n (%) |
|---|---|
| Age (yr) | 42.9±19.9 |
| Sex (male/female) | 47/21 |
| Prodromal infection | 36 (52.9) |
| Hydrocarbon exposure | 6 (8.8) |
| Smoking | 25 (36.8) |
| Hemoptysis | 35 (51.5) |
| Hemoglobin (g/L) | 85.0±24.0 |
| Oliguria/anuria | 17 (25) |
| Urinary protein (g/24 h) | 3.6±3.4 |
| Nephrotic syndrome | 14 (20.6) |
| Gross hematuria | 17 (25) |
| Serum creatinine on diagnosis (μmol/L) | 525.3±292.1 |
| Positive ANCA | 16 (23.5) |
| MPO/PR3-ANCA | 14/2 |
| Level of anti-GBM antibodies (U/ml) | 59.3±36.6 |
| Crescents in glomeruli (%) | 71.9±34.3 |
| Renal survival at 1 yr | 23 (33.8) |
| Patient survival at 1 yr | 52 (76.5) |
N=68 patients. ANCA, antineutrophil cytoplasmic antibody; MPO, myeloperoxidase; PR3, proteinase 3; GBM, glomerular basement membrane.