Table 1.
Clinical characteristics of the study population
| Characteristic | Rejectors (n=29) | Nonrejectors (n=35) | P Value |
|---|---|---|---|
| Mean age (yr) | 50±15 | 54±13 | 0.29 |
| Men | 13 (45) | 10 (29) | 0.20 |
| Ethnic group | 0.40 | ||
| white | 18 (62) | 27 (77) | |
| Hispanic | 9 (31) | 6 (17) | |
| black | 2 (7) | 2 (6) | |
| Donor type | 0.07 | ||
| deceased | 5 (17) | 11 (31) | |
| living related | 14 (48) | 20 (57) | |
| living unrelated | 10 (35) | 4 (11) | |
| Median time after transplant (mo) | 4 (1–27) | 9 (1–48) | 0.34 |
| Time after transplant | 0.82 | ||
| 0–6 mo | 15 (52) | 14 (40) | |
| 6–12 mo | 3 (10) | 5 (14) | |
| 12–24 mo | 3 (10) | 4 (11) | |
| >24 mo | 8 (28) | 12 (34) | |
| Mean serum creatinine at admission (mg/dl) | 2.4±1.0 | 2.5±1.2 | 0.69 |
| Induction therapy | 0.36 | ||
| no induction | 1 (3) | 0 (0) | |
| thymoglobulin | 26 (90) | 30 (86) | |
| IL-2 receptor inhibitor | 2 (7) | 5 (14) | |
| Maintenance immunosuppression | |||
| corticosteroids | 16 (55) | 18 (53) | 1.00 |
| calcineurin inhibitor | 27 (93) | 31 (89) | 0.68 |
| antimetabolite | 27 (93) | 29 (83) | 0.28 |
| rapamycin | 0 (0) | 1 (3) | 1.00 |
Unless otherwise noted, data are the number (percentage) of patients. Data with a plus/minus sign are mean ± SD. Medians are expressed with 25th–75th percentile. Comparisons were performed using unpaired t test, Fisher exact test, chi-squared test, or Mann-Whitney U test.