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. 2011 Dec 6;3(3):571–576. doi: 10.3892/ol.2011.516

Table II.

Characteristics of patients in the CCRT-alone and CCRT plus adjuvant chemotherapy groups.

A, Acute systemic toxicity during CCRT.

Non-extended field
n=18 (%)
Extended field
n=19 (%)
p-value
≥4 cycles of CDDP 14 (78) 13 (68) 0.713
Number of patients with grade 3–4 acute toxicity
 Hematologic toxicity 8 (44) 12 (63) 0.121
  Leukopenia 7 (38) 11 (58)
  Thrombocytopenia 0 (0) 0 (0)
  Anemia 1 (5.3) 3 (16)
 Gastrointestinal toxicity 1 (5.3) 4 (22) 0.153
B, Acute systemic toxicity during adjuvant chemotherapy.

Non-extended field
n=4 (%)
Extended field
n=13 (%)
p-value
Number of patients with grade 3–4 acute hematologic toxicity 4 (100) 13 (100) NS
 Leukopenia 4 (100) 12 (92)
 Thrombocytopenia 0 (0) 3 (23)
 Anemia 0 (0) 7 (54)
C, Late treatment-related toxicities.

CCRT-alone (n=20) CCRT-CTX (n=17)


Grade 1–2 Grade 3–5 Grade 1–2 Grade 3–5
Site of effect
 Gastrointestinal 3 1 2 1
 Genitourinary 0 0 1 0
 Insufficiency fractures 1 0 2 0