Table II.
Up- and down-regulated genes by KBH-A42 treatment in K562 and UM-UC-3 cells.
| GeneBank number | Gene symbol | Fold change vs. control | |
|---|---|---|---|
| K562 | UM-UC-3 | ||
| Up-regulated genes | |||
| NM_015193 | ARC | 7.71 | 2.49 |
| NM_001165 | BIRC3 | 12.25 | 2.23 |
| NM_001252 | CD70 | 5.06 | 1.13 |
| NM_003805 | CRADD | 2.52 | 1.07 |
| NM_003806 | HRK | 5.69 | 0.40 |
| NM_021960 | MCL1 | 3.43 | 0.91 |
| NM_003842 | TNFRSF10B | 5.30 | 2.65 |
| NM_148968 | TNFRSF25 | 10.62 | 7.99 |
| Down-regulated genes | |||
| NM_000633 | BCL2 | 0.35 | 1.39 |
| NM_015367 | BCL2L13 | 0.45 | 1.27 |
| NM_032587 | CARD6 | 0.18 | 0.79 |
| BC010607 | IGF1R | 0.47 | 1.26 |
| NM_013258 | PYCARD | 0.20 | 1.42 |
| NM_032308 | RIP | 0.44 | 1.60 |
| NM_133484 | TANK | 0.41 | 1.38 |
| NM_001243 | TNFRSF8 | 0.14 | 0.76 |
| NM_005426 | TP53BP2 | 0.44 | 1.23 |