Table 2.
Treatment | AVO (Day) | Presence of CL |
---|---|---|
Balb/c | ||
Vehicle Control | 40.5±2.12 | Yes |
PFOA (2.5mg/kg) | 46.4±4.04 * | No |
C57Bl/6 Wild type | ||
Vehicle Control | 40.2±2.25 | Yes |
PFOA (7.5mg/kg) | No opening | No |
C57Bl/6 PPARα−/− | ||
Vehicle Control | 38.98±2.56 | Yes |
PFOA (7.5mg/kg) | 39.21±2.97 | Yes |
Three-week old female Balb/c, C57Bl/6wild type and PPARα knockout mice were treated with vehicle control or PFOA for 4 weeks and sacrificed 24 h after the last treatment.
p< 0.05, compared with Vehicle Control-treated group in each mouse strain.