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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Reprod Toxicol. 2012 Mar 5;33(4):563–576. doi: 10.1016/j.reprotox.2012.02.004

Table 2.

Effect of PFOA treatment on mouse age at vaginal opening (AVO) (mean ± standard deviation, n=5), and ovarian corpora lutea (CL) status.

Treatment AVO (Day) Presence of CL
Balb/c
 Vehicle Control 40.5±2.12 Yes
 PFOA (2.5mg/kg) 46.4±4.04 * No
C57Bl/6 Wild type
 Vehicle Control 40.2±2.25 Yes
 PFOA (7.5mg/kg) No opening No
C57Bl/6 PPARα−/−
 Vehicle Control 38.98±2.56 Yes
 PFOA (7.5mg/kg) 39.21±2.97 Yes

Three-week old female Balb/c, C57Bl/6wild type and PPARα knockout mice were treated with vehicle control or PFOA for 4 weeks and sacrificed 24 h after the last treatment.

*

p< 0.05, compared with Vehicle Control-treated group in each mouse strain.