Table 2.
Effect of nephrectomy (Nx) on urine output of polyuric patientsa
| Nephrectomy | Patients (n)a | Median urine output (range)b | ||
|---|---|---|---|---|
| Pre-Nx (ml/kg/h) | Post-Nx (ml/kg/h) | % Differencec | ||
| Unilateral | 9 | 3.79 (1.43– .87) | 2.22 (0.57–5.00) | −34* (−24 to −72) |
| Bilateral, first stage | 6 | 4.08 (3.11–6.03) | 2.39 (1.90–3.45) | −42* (−20 to −55) |
| Bilateral, second stage (rendered anuric) | 7 | 2.87 (1.85–6.13 ) | – | – |
| Bilateral, synchronous (rendered anuric) | 4 | 7.62 (3.81–8.98) | – | – |
*p < 0.05
–, Not applicable
CAKUT, congenital anomalies of the kidney and urinary tract
aUnilateral nephrectomy: CAKUT (n = 3 patients), cystinosis (5), chronic interstitial nephritis (1). Bilateral, staged nephrectomy: CAKUT (6), Bartter syndrome (1). Bilateral, synchronous nephrectomy: cystinosis (4). Unilateral nephrectomies at the time of KT were excluded. Some patients had additional indications leading to nephrectomy (see Material and methods)
bUrine output number reflects last documented collection prior to Nx. See Material and methods for polyuria definition. Decision to operate was based on a combination of psychosocial and medical factors
cWilcoxon matched-pairs signed-rank test