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. 2012 May 30;2:53. doi: 10.3389/fonc.2012.00053

Table 1.

Characteristics of tumor samples included in the study.

Patient ID Tumor type WHO Grade Location Sex Age (years) Seizure Fresh tissue sample RIN Primary culture RIN
168 AM II Fronto-temporal region F 13 No 8.0 9.3
186 PA I Cerebellum M 7 No 7.7 9.2
192 PA I Cerebellum M 6 No 2.5 8.4
224 AO III Right rolandic region F 30 No 8.2 9.5
232 E II Right frontal region F 11 No 7.8 N/A
234 GBM IV Giant, left hemisphere F 8 months No 6.9* 9.1
250 PA I Cerebellum F 11 No 6.2 N/A
1001 AG I Left parieto-occipital region F 10 Yes 2.4 9.0
0102 PA I Cerebellum M 20 No 2.2 9.5
1002 PA I Cerebellum M 10 No 7.3 8.1

All the samples included in the study are reported. AO (sample 224), PA (sample 186), AM (sample 168), and PA (sample 1001) were used for the GEP comparison between fresh tissue samples and their derived primary cultures (see Figure 1). The other analysis referred to glioma cohort were carried out only on samples with the best RIN value (in bold) and were performed in all the tumor types listed in the Table, excepted for the meningioma (AM, sample 168). Abbreviations: PA, pilocytic astrocytoma; AO, anaplastic oligodendroglioma; GBM, glioblastoma multiforme; E, ependymoma; AM, atypical meningioma; AG, angiocentric glioma; F, female; M, male; N/A, not available.

*For the determination of GEP of GBM sample the fresh tissue was used in the bioinformatic analyses because, despite the best RIN value, the RNA obtained from the short-term culture was not sufficient to perform microarray experiment.