Table 3.

Statistically significant biological processes, associated to the downregulated genes only, represented by DE GO terms in our cohort of glioma samples.

Biological processes	GO terms	Representative genes	Fold change
Neuronal phenotype	GO:0019226 ∼ transmission of nerve impulse	KCNMA1 (variant 1)	−2.82
	GO:0007268 ∼ synaptic transmission	SLC1A2	−2.84
	GO:0030182 ∼ neuron differentiation	SCN2B	−3.01
	GO:0031644 ∼ regulation of neurological system process	SCN4B	−2.82
	GO:0051969 ∼ regulation of transmission of nerve impulse	NEUROD2	−7.74
	GO:0050804 ∼ regulation of synaptic transmission	STMN2	−8.49
	GO:0048666 ∼ neuron development
Ion transport	GO:0030001 ∼ metal ion transport	KCNMA1 (variant 1)	−2.82
	GO:0006811 ∼ ion transport	CACN2D2	−2.27
	GO:0006812 ∼ cation transport	ATP1B1	−4.60
		SCN2B	−3.01
		SCN4B	−2.82
		SLC30A3	−4.08
		ATP6V1G2	−4.49
		ATP6V0C	−2.11
		SLC26A1	−3.15
		SLCO4A1	−2.45
		SLC4A3	−2.52

Some representative genes are reported with the corresponding fold change.