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. 2012 Jun;40(6):1138–1143. doi: 10.1124/dmd.111.042432

TABLE 1.

Compounds that induced inward currents in PMAT-expressing oocytes

Data represent means ± S.D. for two to three independent experiments. Perfusion buffer: NaCl buffer; substrate concentration: 2.5 mM.

Compounds Current
pH 6.0 pH 7.5
nA
Histamine −110 ± 10.3 −30.5 ± 9.19
MPTP −62.7 ± 8.26 −5.67 ± 3.53
Nicotine −75.7 ± 14.3 −6.30 ± 1.24
Metformin −38.0 ± 2.92 −2.02 ± 0.50
Amantadine −21.2 ± 4.73 −7.26 ± 0.74
TEA+ −11.7 ± 1.00 −0.627 ± 1.79