. 2012 May 30;2:430. doi: 10.1038/srep00430

Table 1. Biochemical measurements in plasma and feces of control and Colestilan-treated TGR5^+/+ and TGR5^−/− mice.

	TGR5 ^+/+	TGR5 ^+/+	TGR5^−/−	TGR5^−/−
	Control	Colestilan	Control	Colestilan
Final body weight (g)	58.94 ± 0,93	53.84 ± 0,77^a	58.61 ± 1,94	53.71 ± 2,09^a
Plasma
LDL-cholesterol (mM)	0.42 ± 0.02	0.35 ± 0.03^a	0.39 ± 0.05	0.32 ± 0.03
HDL-cholesterol (mM)	4.50 ± 0.16	4.43 ± 0.21	4.49 ± 0.22	4.22 ± 0.19
Total cholesterol (mM)	5.48 ± 0.14	5.19 ± 0.20	5.55 ± 0.32	5.03 ± 0.24
Feces
Fecal weight (mg/day/g BW)	12.30 ± 3.54	33.08 ± 3.23^a	11.87± 2.35	30.39 ± 4.23^a
Glycerol derivatives (μg/mg)	0.18 ± 0.02	0.58 ± 0.09^a	0.24 ± 0.03	0.60 ± 0.09^a
Total cholesterol (μg/mg)	3.88 ± 1.23	4.23 ± 0.91	3.23 ± 1.78	3.98 ± 1.23
Free fatty acids (μg/mg)	5.45 ± 1.56	10.34 ± 2.34^a	6.23 ± 1.34	11.19 ± 3.29^a
Phospholipids (μg/mg)	3.39 ± 0.62	7.98 ± 1.92^a	11.13 ± 3.23^b	9.29 ± 0.43
Total bile acids (μmol/g)	4.09 ± 1.10	10.29 ± 0.98^a	2.22 ± 0.34^b	6.87 ± 1.23a,b

Colestilan 2% was supplemented in the diet for 2 weeks after 12 weeks of high fat feeding. Values represent mean ± SE.

^aStatistically significant as compared to corresponding control group, p<0.05.

^bStatistically significant between genotypes, p<0.05.

Table 1. Biochemical measurements in plasma and feces of control and Colestilan-treated TGR5+/+ and TGR5−/− mice.