Table 1.
L-domains found in enveloped virus proteins, which bud from the cell membrane in an ESCRT-dependent process: Lassa fever virus (LFV) [39], lymphocytic choriomeningitis virus (LCMV) [39, 40], Ebola virus (EboV) [2], Marberg virus (MarV) [41], hepititus B virus (HBV) [42], Herpes simplex virus, type 1 (HSV-1) [43], Simian virus, type 5 (SV5) [44], Mumps virus (MuV) [45], avian sarcoma leukemia virus (ASLV) [11, 14, 15], human immunodeficiency virus, type 1 (HIV-1) [2, 10, 27], human T-lymphotropic virus, type 1 (HTLV-1) [2], equine infectious anemia virus (EIAV) [12, 16], vesicular stomatitis virus (VSV) [46], and rabies virus (RV) [47].
| Virus species | Virus | Protein | Amino acid sequence containing L-domain |
|---|---|---|---|
| Arenavirus | LFV | Z | AAPTAPPTGAADSIPPPYSP |
| LCMV | Z | TAPSSPPPYEE | |
|
| |||
| Filovirus | EboV | VP40 | MRRVILPTAPPEYMEAI |
| MarV | VP40 | NTYMQYLNPPPYADHS | |
|
| |||
| Hepadnavirus | HBV | Core protein | PPAY |
|
| |||
| Herpesvirus | HSV-1 | E | PPTY |
|
| |||
| Paramyxovirus | SV5 | M | QSIKAFPIVINSDG |
| MuV | M | RLNA FPIVMGQ | |
|
| |||
| Retrovirus | ASLV | p2B of Gag | ATASAPPPPYVGSGLYPSL |
| HIV-1 | p6 of Gag | PEPTAPPFLQSRPEPTAPPEES..ELYPLTSLR | |
| HTLV-I | MA of Gag | DPQIPPPYVEPTAP | |
| EIAV | p9 of Gag | QNLYPDLSEIK | |
|
| |||
| Rhabdovirus | VSV | M | LGIAPPPYEEDTSMEYAPSAP |
| RV | M | DDLWLPPPEYVPLKEL | |