Table 2.
Response | RECIST 1.1 | Choi |
---|---|---|
PD | Increase of at least 20% and 5 mm in SLD | Increase of at least 10% in SLD and decrease of less than 15% in MLDa |
New lesion(s) | New lesion(s) | |
Unequivocal progression of non-target lesion(s) | New or increasing nodule(s) within a mass | |
SD | Decrease of less than 30% and increase of less than 20% in SLD | Decrease of less than 10% and increase of less than 10% in SLD and decrease of less than 15% in MLDa |
PR | Decrease of at least 30% in SLD | Decrease of at least 10% in SLD and decrease of at least 15% in MLDa |
CR | Complete remission | Complete remission |
PD, progressive disease; SD, stable disease; PR, partial complete response; CR, complete response; SLD, sum of the longest diameter according to RECIST[9]; MLD, mean lesion density according to modified CT criteria[11].
aComplementary recommendation of the German GIST Working Group: density changes should account for at least 10 HU.