TABLE 1.
Effects of H2S on isoflurane-induced loss of righting reflex
Isoflurane in 21% Oxygen | Isoflurane + 80 ppm H2S in 21% Oxygen | Isoflurane + 250 ppm H2S in 21% Oxygen | |
---|---|---|---|
EC50, %atm | 0.89 | 0.81*** | 0.67*** |
95% confidence interval for EC50, %atm | 0.87–0.90 | 0.80–0.82 | 0.62–0.72 |
Hill slope | 26 | 27 | 11* |
95% confidence interval for Hill slope | 18–35 | 19–35 | 2–20 |
, P < 0.05;
, P < 0.001 with respect to isoflurane alone.