TABLE 2.
Annual Percent Change From Joinpoint Regression Models for Childhood Cancers Diagnosed in Children Aged 0 to 4 Years in SEER 9 Catchment Areas in 1986–2008
Cancer | Years | APC1a | 95% CI | Years | APC2a | 95% CI |
---|---|---|---|---|---|---|
All cancers | 1986–2008 | 0.2 | −0.2 to 0.7 | |||
I Leukemias; myeloproliferative and myelodysplastic diseases | 1986–2008 | 0.4 | −0.2 to 1.1 | |||
I(a) Lymphoid leukemias | 1986–2008 | 0.3 | −0.3 to 1.0 | |||
I(b) Acute myeloid leukemias | 1986–2008 | 1.7 | −0.2 to 3.6 | |||
III CNS and miscellaneous intracranial and intraspinal neoplasms | 1986–2008 | 0.1 | −0.5 to 0.7 | |||
III(a.1) Ependymomas | 1986–2008 | −2.7b | −4.5 to −0.9b | |||
III(b) Astrocytomas | 1986–2008 | 0.5 | −0.8 to 1.8 | |||
III(c.1) Medulloblastomas | 1986–2008 | 0.5 | −1.6 to 2.7 | |||
III(c.2) PNET | 1986–1993 | 11.5 | −5.0 to 31.0 | 1993–2008 | −7.4b | −12.1 to −2.4b |
IV(a) Neuroblastoma and ganglioneuroblastoma | 1986–2008 | 0.4 | −0.7 to 1.4 | |||
V Retinoblastoma | 1986–2008 | −0.8 | −2.1 to 0.6 | |||
VI(a.1) Nephroblastoma (Wilms tumor) | 1986–1997 | 2.2 | −1.2 to 5.8 | 1997–2008 | −4.0b | −7.3 to −0.6b |
VII(a) Hepatoblastoma | 1986–2008 | 2.1b | 0.2 to 4.0b | |||
IX(a) Rhabdomyosarcomas | 1986–2008 | −0.1 | −1.8 to 1.7 | |||
X Germ cell and trophoblastic tumors; neoplasms of gonads | 1986–2008 | 0.7 | −1.2 to 2.6 |
APCs calculated via weighted least-squares regression.
Trend is statistically significant (P < .05).