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. 2012 Jun;129(6):1125–1133. doi: 10.1542/peds.2011-3418

TABLE 2.

Annual Percent Change From Joinpoint Regression Models for Childhood Cancers Diagnosed in Children Aged 0 to 4 Years in SEER 9 Catchment Areas in 1986–2008

Cancer Years APC1a 95% CI Years APC2a 95% CI
All cancers 1986–2008 0.2 −0.2 to 0.7
I Leukemias; myeloproliferative and myelodysplastic diseases 1986–2008 0.4 −0.2 to 1.1
 I(a) Lymphoid leukemias 1986–2008 0.3 −0.3 to 1.0
 I(b) Acute myeloid leukemias 1986–2008 1.7 −0.2 to 3.6
III CNS and miscellaneous intracranial and intraspinal neoplasms 1986–2008 0.1 −0.5 to 0.7
 III(a.1) Ependymomas 1986–2008 −2.7b −4.5 to −0.9b
 III(b) Astrocytomas 1986–2008 0.5 −0.8 to 1.8
 III(c.1) Medulloblastomas 1986–2008 0.5 −1.6 to 2.7
 III(c.2) PNET 1986–1993 11.5 −5.0 to 31.0 1993–2008 −7.4b −12.1 to −2.4b
IV(a) Neuroblastoma and ganglioneuroblastoma 1986–2008 0.4 −0.7 to 1.4
V Retinoblastoma 1986–2008 −0.8 −2.1 to 0.6
VI(a.1) Nephroblastoma (Wilms tumor) 1986–1997 2.2 −1.2 to 5.8 1997–2008 −4.0b −7.3 to −0.6b
VII(a) Hepatoblastoma 1986–2008 2.1b 0.2 to 4.0b
IX(a) Rhabdomyosarcomas 1986–2008 −0.1 −1.8 to 1.7
X Germ cell and trophoblastic tumors; neoplasms of gonads 1986–2008 0.7 −1.2 to 2.6
a

APCs calculated via weighted least-squares regression.

b

Trend is statistically significant (P < .05).

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