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Unfolding a section of the N-terminus including the first β-strand within BtuB should open a pore that enables the passage of substrate. On the left a) is a view from the periplasmic surface of BtuB in its folded state where residues 6 to 65 are highlighted in blue. On the right is a view of the periplasmic surface b) with the first 65 residues removed from the core of the protein.
