Table 2.
Baseline maternal characteristics of pregnant women using insulin glargine versus NPH among the studies selected for meta-analysis.
| Maternal characteristic |
Number of studies | Insulin glargine | NPH | Mean difference* |
95% confidence limits | |||
|---|---|---|---|---|---|---|---|---|
| Unadjusted mean/events | Number of Patients |
Unadjusted mean/events | Number of Patients |
Lower limit | Upper limit | |||
| Maternal age (yrs) | 7 | 30.3 | 289 | 30.5 | 322 | −0.49 | −1.87 | 0.89 |
| Duration of diabetes (yrs) | 7 | 10.2 | 250 | 10.3 | 278 | 1.14 | 0.28 | 2.00 |
| Type 1 diabetes | 5 | 15.4 | 117 | 14.6 | 133 | 1.67 | 0.82 | 2.52 |
| Pregestational diabetes | 3 | 6.1 | 140 | 6.4 | 146 | 0.69 | −0.96 | 2.35 |
| Prepregnancy weight (kg) | 4 | 82.0 | 154 | 80.1 | 190 | 1.53 | −2.21 | 5.27 |
| Prepregnancy BMI (kg/m2) | 3 | 31.0 | 140 | 29.7 | 139 | −0.46 | −1.81 | 0.90 |
*Mean difference: insulin glargine versus NPH insulin.