Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Signaling pathways involved in IL-4-induced DC-SIGN expression on THP-1 cells. ERK signaling pathway plays a main role by transcription factor of Ets-1 to active DC-SIGN promoter. JAK-STAT and NF-κB signaling pathways are also involved, which may be induced by IL-4/IL-4R directly or by the interactions with ERK pathway indirectly.
