Intracellular Th1 and Th2 cytokines. (A–D) Box and whiskers plot of (A) percentage of interferon-gamma (IFN-γ) producing cells; (B) percentage of IL-4 producing cells; and (C) the ratio of Th1/Th2 cytokine (interferon-gamma [IFN-γ] and IL-4) determined by Fast Immune Cytokine System for normal controls (n = 30) and asthmatic patients (n = 39). The medians are indicated by a line inside each box, the 25th and 75th percentiles are indicated by the box limits, and the lower and upper error bars represent the 10th and 90th percentiles, respectively. The mean values were compared and the P values are indicated at the figure. (D) Correlation between Th1/Th2 ratio and vitamin D levels in asthmatic patients using Pearson’s correlation coefficient.
Note: Mann–Whitney rank sum test assessed the differences between controls and patients.
Abbreviation: IL, interleukin.