Table 3.
Properties of surfaces that affect protein adsorption [80].
feature | effect |
---|---|
topography | greater texture exposes more surface area for interaction with proteins |
composition | chemical makeup of a surface will determine the types of intermolecular forces governing interaction with proteins |
hydrophobicity | hydrophobic surfaces tend to bind more protein |
heterogeneity | non-uniformity of surface characteristics results in domains that can interact differently with proteins |
potential | surface potential will influence the distribution of ions in solution and interaction with proteins |