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. 2012 Mar 22;2(3):259–277. doi: 10.1098/rsfs.2012.0012

Table 3.

Properties of surfaces that affect protein adsorption [80].

feature effect
topography greater texture exposes more surface area for interaction with proteins
composition chemical makeup of a surface will determine the types of intermolecular forces governing interaction with proteins
hydrophobicity hydrophobic surfaces tend to bind more protein
heterogeneity non-uniformity of surface characteristics results in domains that can interact differently with proteins
potential surface potential will influence the distribution of ions in solution and interaction with proteins