Figure 4.

Photographs (pictures, upper left panel), haemoglobin contents (solid columns, upper left panel), and histology of Matrigel plugs indicating increased neovascularization following S100A8 or S100A9 protein treatment. Matrigel mixed with PBS was the negative control group, and FGF plus heparin was the positive control group. Haemoglobin content of Matrigel plugs (mean ± standard deviation, n = 4) was expressed as the amount of haemoglobin per gram of Matrigel plug. Microscopic examination of the same Matrigel plugs showed inflammatory cells and vascular structures (arrowheads). Shown are representations of two experiments with similar results.