Table 1.
Genetic architecture for classical conditioning (simple or complex models) and sensitization of the PER
| Classical conditioning
|
Sensitization
|
||||
|---|---|---|---|---|---|
| Complex
|
Simple
|
||||
| Parameter | Estimate | Parameter | Estimate | Parameter | Estimate |
| Mid | 40.7 ± 2.5 | Mid | 34.2 ± 0.8 | Mid | 47.4 ± 0.7 |
| a | 22.4 ± 1.1 | a | 22.5 ± 1.1 | a | 22.0 ± 1.1 |
| d | 39.3 ± 5.6 | d | 61.9 ± 13.8 | d | — |
| a·a | — | a·a | 15.8 ± 5.7 | a·a | — |
| a·d | −19.8 ± 4.1 | a·d | −23.4 ± 3.9 | a·d | — |
| d·d | −14.9 ± 4.9 | d·d | −24.0 ± 8.5 | d·d | — |
| am | — | Sex | 1.9 ± 0.5 | ||
| dm | — | ||||
| ax | — | ||||
| dx | 14.2 ± 4.1 | ||||
| ax·ax | — | ||||
| ax·dx | −14.4 ± 5.7 | ||||
| dx·dx | — | ||||
| aax·aax | 18.3 ± 4.4 | ||||
| aax·dax | — | ||||
| axa·dxa | — | ||||
| dax·dax | — | ||||
| Sex | 8.2 ± 1.8 | ||||
The genetic parameters estimated are as follows: Mid, midparent value between high and low strains; a, additive value; d, dominance value; am, additive maternal value; dm, dominance maternal value; ax, X-linked additive value; dx, X-linked dominance value; sex, sex-limited effect; a·a, a·d, etc., two-way epistatic interactions among additive or dominance values.